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Biomedicum Helsinki Day and Professor George Klein

Program of Biomedicum Helsinki Day

September 21, 2009,  Biomedicum Helsinki
Host: Olli A. Jänne, Director of Biomedicum Helsinki

10:00-11:30, Lecture Hall 3

Professor Klein's special talk to aspiring young scientists
Short history of a molecular cancer biology and elements of  discovery

The 2009 Biomedicum Helsinki Lecture

12:00-13:00 , Lecture Hall 1

Professor George Klein: Towards a genetics of cancer resistance

Presentations by Young Scientists

Lecture Hall 1

13:00-13:15  Anna Kotronen: Insulin resistance and non-alcoholic fatty liver disease in man

13:15-13:30 Laura Mikkonen: Sumo1 knockout animals exhibit metabolic and  tumorigenic phenotypes under stressed conditions

13:30-13:45  Kari Vaahtomeri: AMPK mediates a specific subset of LKB1  responses in mesenchymal cells

13:45-14:00 Biomedicum Helsinki Foundation Young Scientist Prize lecture                                            
Johanna Partanen: The role of epithelial organization in tumor suppression

PROFESSOR GEORGE KLEIN

Biomedicum Helsinki Foundation, Genome-Scale Biology Research and Molecular Cancer Biology Research Programs of the Faculty of Medicine, University of Helsinki, will host Professor George Klein's visit at Biomedicum Helsinki on the Biomedicum Helsinki Day, September 21, 2009.

Professor George Klein from Karolinska Institutet will visit Biomedicum Helsinki on September 21st, 2009 to deliver the 2009 Biomedicum Helsinki Lecture. He will give actually two talks on that day. In his first talk, Professor Klein gives a perspective talk presenting foundations of molecular cancer biology and elements of discovery in scientific research. He will discuss topics including historical milestone discoveries in cancer research, basic elements of discovery - mind-set, timing, environment and the important questions still unanswered in the field. This talk will target aspiring scientists at any stage of their careers - students, junior and senior scientists. Students participating in the seminar will be eligible for credits (applied) through Helsinki Biomedical Graduate School.

Professor Klein's second talk will be the 2009 Biomedicum Helsinki Lecture entitled "Towards a genetics of cancer resistance". The entire program of the Biomedicum Helsinki Day is shown below.

Professor (emeritus) George Klein from Karolinska Institutet is one of the world's foremost cancer biologists. Born 1925 in Budapest, Hungary, he has worked in the field of cancer research since 1947 and his stunning publication record today encompasses over 1300 papers. Professor Klein was the founder and director of the Department of Tumor Biology at the Karolinska Institute (established in 1957, now part of Microbiology and Tumor Biology Center, MTC). He was a member of the Nobel Assembly between 1957 and 1993 and is a foreign member of the National Academy of Sciences of the United States as well as of many other prestigious academies and societies. Professor Klein is still an active research group leader at MTC, a productive scientist and an authoritative commentator in the field of cancer biology. George Klein is also a dynamic writer outside of the field of science, and his non-scientific contributions comprise now 13 books; the best known of the latter ones being "The Atheist and the Holy City" and "Pieta".

Recent publications

Klein G. Toward a genetics of cancer resistance. Proc Natl Acad Sci USA. 2009; 106: 859-863.

Kashuba E, Yurchenko M, Yenamandra SP, Snopok B, Isaguliants M, Szekely L, Klein G. EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes. Proc Natl Acad Sci USA. 2008; 105: 5489-5494.

Klein G, Imreh S, Zabarovsky ER. Why do we not all die of cancer at an early age? Adv Cancer Res. 2007; 98:1-16. Review.

Klein G. Epigenetics: surveillance team against cancer. Nature. 2005;43:150.

Klein G, Klein E. Surveillance against tumors--is it mainly immunological? Immunol Lett. 2005; 100: 29-33. Review.

Klein G. Perspectives in studies of human tumor viruses. Front Biosci. 2002; 7:d268-274. Review.

Biomedicum Helsinki Day and Professor George Klein

Program of Biomedicum Helsinki Day

September 21, 2009,  Biomedicum Helsinki
Host: Olli A. Jänne, Director of Biomedicum Helsinki

10:00-11:30, Lecture Hall 3

Professor Klein's special talk to aspiring young scientists
Short history of a molecular cancer biology and elements of  discovery

The 2009 Biomedicum Helsinki Lecture

12:00-13:00 , Lecture Hall 1

Professor George Klein: Towards a genetics of cancer resistance

Presentations by Young Scientists

Lecture Hall 1

13:00-13:15  Anna Kotronen: Insulin resistance and non-alcoholic fatty liver disease in man

13:15-13:30 Laura Mikkonen: Sumo1 knockout animals exhibit metabolic and  tumorigenic phenotypes under stressed conditions

13:30-13:45  Kari Vaahtomeri: AMPK mediates a specific subset of LKB1  responses in mesenchymal cells

13:45-14:00 Biomedicum Helsinki Foundation Young Scientist Prize lecture                                            
Johanna Partanen: The role of epithelial organization in tumor suppression

PROFESSOR GEORGE KLEIN

Biomedicum Helsinki Foundation, Genome-Scale Biology Research and Molecular Cancer Biology Research Programs of the Faculty of Medicine, University of Helsinki, will host Professor George Klein's visit at Biomedicum Helsinki on the Biomedicum Helsinki Day, September 21, 2009.

Professor George Klein from Karolinska Institutet will visit Biomedicum Helsinki on September 21st, 2009 to deliver the 2009 Biomedicum Helsinki Lecture. He will give actually two talks on that day. In his first talk, Professor Klein gives a perspective talk presenting foundations of molecular cancer biology and elements of discovery in scientific research. He will discuss topics including historical milestone discoveries in cancer research, basic elements of discovery - mind-set, timing, environment and the important questions still unanswered in the field. This talk will target aspiring scientists at any stage of their careers - students, junior and senior scientists. Students participating in the seminar will be eligible for credits (applied) through Helsinki Biomedical Graduate School.

Professor Klein's second talk will be the 2009 Biomedicum Helsinki Lecture entitled "Towards a genetics of cancer resistance". The entire program of the Biomedicum Helsinki Day is shown below.

Professor (emeritus) George Klein from Karolinska Institutet is one of the world's foremost cancer biologists. Born 1925 in Budapest, Hungary, he has worked in the field of cancer research since 1947 and his stunning publication record today encompasses over 1300 papers. Professor Klein was the founder and director of the Department of Tumor Biology at the Karolinska Institute (established in 1957, now part of Microbiology and Tumor Biology Center, MTC). He was a member of the Nobel Assembly between 1957 and 1993 and is a foreign member of the National Academy of Sciences of the United States as well as of many other prestigious academies and societies. Professor Klein is still an active research group leader at MTC, a productive scientist and an authoritative commentator in the field of cancer biology. George Klein is also a dynamic writer outside of the field of science, and his non-scientific contributions comprise now 13 books; the best known of the latter ones being "The Atheist and the Holy City" and "Pieta".

Recent publications

Klein G. Toward a genetics of cancer resistance. Proc Natl Acad Sci USA. 2009; 106: 859-863.

Kashuba E, Yurchenko M, Yenamandra SP, Snopok B, Isaguliants M, Szekely L, Klein G. EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes. Proc Natl Acad Sci USA. 2008; 105: 5489-5494.

Klein G, Imreh S, Zabarovsky ER. Why do we not all die of cancer at an early age? Adv Cancer Res. 2007; 98:1-16. Review.

Klein G. Epigenetics: surveillance team against cancer. Nature. 2005;43:150.

Klein G, Klein E. Surveillance against tumors--is it mainly immunological? Immunol Lett. 2005; 100: 29-33. Review.

Klein G. Perspectives in studies of human tumor viruses. Front Biosci. 2002; 7:d268-274. Review.